RNA Details
Disease Name
nephritis interstitia
Tissue
kidney
RNA Symbol
mir-140
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
dual-luciferase reporter assay
Target
TGFBR
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-140-5p Mediates Renal Fibrosis Through TGF-beta1/Smad Signaling Pathway by Directly Targeting TGFBR1
Year
2020
Function
miR-140-5p may have a therapeutic potential for preventing fibrotic kidney diseases through inhibiting the TGF-beta/smad signaling pathway by directly targeting TGF-betaR1.